FXPOI, or fragile X-associated primary ovarian insufficiency, is one of three known Fragile X-associated Disorders (FXD). All the FXD are caused by changes in the FMR1 Gene.
What Is FXPOI?
FXPOI is a condition in which the ovaries are not functioning at full capacity in an FMR1 premutation carrier. Common symptoms of FXPOI include absent or irregular periods, symptoms of menopause such as hot flashes, etc, early menopause and infertility.

http://www.fragilex.org/fragile-x-associated-disorders/fxpoi/